Actinomycetes, Vol. 6, Part 2, 1995
MUTAGEN - INDUCED CHANGES IN CELL COMPONENTS AND
BIOSYNTHESIS OF ANTIBIOTIC 1012 IN STREPTOMYCES
SPECTABILIS
V. IVANOVA, R. ROUSEVA, M. NAIDENOVA, R. RACHEV and M.
KOLAROVA
Code Number: AC95008
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Text: 26K
Graphics: Line Drawings (gif) 49K
Photos (jpg) 51K / Halftones (gif) 58K
ABSTRACT. Twelve actinomycete strains (parent organisms,
mutants and a fusant) of Streptomyces spectabilis were
investigated with reference to the biosynthesis of antibiotic
complex 1012. Mutant H-72, obtained by UV radiation, exhibited
the highest productivity of the antibiotic complex.
Correlation between production of complex 1012 and
biosynthesis of cell structural components (lipids,
polysaccharides and proteins) was investigated.
Copyright 1995 CETA