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Indian Journal of Dermatology, Venereology and Leprology
Medknow Publications on behalf of The Indian Association of Dermatologists, Venereologists and Leprologists (IADVL)
ISSN: 0378-6323 EISSN: 0378-6323
Vol. 77, No. 5, 2011, pp. 587-590
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Bioline Code: dv11170
Full paper language: English
Document type: Case Report
Document available free of charge
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Indian Journal of Dermatology, Venereology and Leprology, Vol. 77, No. 5, 2011, pp. 587-590
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Langerhans cell histiocytosis: An uncommon presentation, successfully treated by thalidomide
Shahidi-Dadras, Mohammad; Saeedi, Mohammad; Shakoei, Safoura & Ayatollahi, Azin
Abstract
Langerhans cell histiocytosis (LCH) is a rare disease and generally affects children under 15
years of age. Adult onset form and cutaneous features at presentation are uncommon. There
are some options for treatment of the skin lesions of LCH such as topical and intralesional
corticosteroid, nitrogen mustard, etc., which are not completely curative. Herein, we report
a case of perianal LCH in a 20-year-old man with one-year history of recalcitrant welldemarcated,
erythematous, and ulcerated plaque surrounding the anal orifice, with pain and
difficulty in defecation that was successfully treated with thalidomide.
Keywords
Cutaneous, Langerhans cell histiocytosis, perianal lesion, thalidomide
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© Copyright 2011 Indian Journal of Dermatology, Venereology, Leprology. Alternative site location: http://www.ijdvl.com
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