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Association of Mean Platelet Volume With The Degree of Retinopathy in Patients with Diabetes Mellitus
Ateş, Orhan; Kiki, İlhami; Bilen, Habip; Keleş, Mustafa; Koçer, İbrahim; Kulaçoğlu, Destan Nil & Baykal, Orhan
Abstract
Aim:
We investigated the association of mean platelet volume
(MPV) with the degree of retinopathy in patients with diabetes
mellitus (DM).
Methods:
Ninety patients with diabetic retinopathy (DRP) and 30
healthy individuals were included in the study. Diabetic patients
included 30 background, 30 non-proliferative and 30 proliferative
diabetic retinopathy cases. Complete blood count, intra- and intergroup
comparisons of MPV values were performed.
Results:
Mean values for MPV in patients with background, nonproliferative
and proliferative DRP were 7.76±0.72 fL, 7.94±0.61
fL and 8.18±0.89 fL, respectively. MPV values of patients with
background DRP was not significantly different from that of the
control group and patients with non-proliferative and proliferative
DRP as well. However, MPV values of patients with proliferative
DRP were significantly higher than the values of control group
(p< 0.05). A significant correlation was found between the degree
of retinopathy and mean values of MPV in diabetic patients (r=
0.214, p< 0.05).
Conclusions:
We found an association between the degree of retinopathy
and mean values of MPV. This finding suggests a role for
platelets in the pathogenesis of vascular complications and that
mean platelet volume would be useful in monitoring the disease
progression.
Keywords
Diabetes mellitus, retinopathy, mean platelet volume
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