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African Health Sciences
Makerere University Medical School
ISSN: 1680-6905
EISSN: 1680-6905
Vol. 14, No. 1, 2014, pp. 261-266
Bioline Code: hs14040
Full paper language: English
Document type: Research Article
Document available free of charge

African Health Sciences, Vol. 14, No. 1, 2014, pp. 261-266

 en The importance of the mean platelet volume in the diagnosis of supraventricular tachycardia
Tarık, Ocak; Alim, Erdem; Arif, Duran; Ümit, Yaşar Tekelioğlu; Serkan, Öztürk; Suzi, Selim Ayhan; Mehmet, Fatih Özlü & Mehmet, Yazıcı

Abstract

Background: The diagnosis of palpitation can be difficult in the emergency department (ED) and the waiting time for a first appointment with an arrhythmia clinic can be very long. The inflammation is sufficient to facilitate the initiation of supraventricular tachyarrhythmia (SVT). The increased mean platelet volume (MPV) is closely correlated with inflammation and to reflect inflammatory burden in different condition.
Objective: In this study, we aimed to investigate the relation between MPV and SVT in patient with documented atrial tachyarrhythmia in ED.
Methods: Two study groups were compared; a SVT group with arrive at the ED with documented SVT (n=122) and 100 healthy adult without any palpitation symptom, arrhythmic disease, and with normal physical examination results that were brought for checkups to the cardiology polyclinic were classified as control group. Blood samples were obtained from all patients for determining the hematologic counts and MPV during first hour in ED period.
Results: In terms of the focus of the study, hemoglobin, neutrophil count, mean cell volume (MCV), red cell distribution width (RDW), platelet, white blood cell (WBC), and lymphocyte counts were similar in both group (p>0.05). MPV in the SVT group was signifi cantly higher than in the control group (9.12±1.22 fl vs 8.64±0.89 fl , p<0.001). Multivariate logistic regression analysis showed that just MPV was independent predictor of SVT in patients with palpitation in ED (odds ratio [OR] 8.497, 95% confidence interval (6.181 to 12.325), p=0.012).
Conclusions: Our study described that MPV is helpful parameter for the diagnosis of SVT in emergency department, for the first time in the literature.

Keywords
mean platelet volume; inflammation; palpitation; supraventricular tachycardia; diagnostic

 
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