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Journal of Applied Sciences and Environmental Management
World Bank assisted National Agricultural Research Project (NARP) - University of Port Harcourt
ISSN: 1119-8362
Vol. 9, No. 3, 2005, pp. 77-80 		Bioline Code: ja05062
Full paper language: English
Document type: Research Article
Document available free of charge

Journal of Applied Sciences and Environmental Management, Vol. 9, No. 3, 2005, pp. 77-80

 en Anti-Oxidant Protective Effects of Cassia alata check for this species in other resources in Rats Exposed to Carbon Tetrachloride
WEGWU, M O; AYALOGU, E O; SULE, O J

Abstract

The protective activity of Cassia alata check for this species in other resources against carbon tetrachloride (CCl4) - induced hepatotoxicity in rats was assessed. Crude extracts of petals of the plant in 0.5% ethanol were administered by intubation for 14 days prior to injection of 0.5ml Kg-1 CCl4 into the rats. Serum aspartate aminotransferase and alanine aminotransferase levels, 18 hours after CCl4 administration, decreased significantly (P ≤ 0.05) in rats treated with the extracts than in CCl4 - treated rats only. These findings suggest that Cassia alata may be protective against hepatotoxin-induced liver damage in rats.@JASEM

 
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