A set of six novel benzimidazoles compounds were prepared, this includes 5-
Nitro-2-phenyl -1-ethylbenzimidazol (
5),2-(p-Bromophenyl)-5-nitro-1-ethylbenzimidazol (
6), 2- (p-
Bromophenyl- 5-nitro-1–cyclopentylbenzimidazol(
7),2-(p-Bromophenyl)-5-nitro-1-
cyclopentylbenzimidazol (
8),5-Amino-2-(p-Bromophenyl)-1-ethylbenzimidazol (
9), and 5-Amino-
(2- (p- Bromophenyl)- 1- cyclopentylbenzimidazol (
10). The chemical structures of these
compounds were elucidated using NMR and elemental analysis. The biological activity of these
compounds as fungicides was tested against three commercially known fungicides (
Candida albicans
,
patient isolate
Candida glabrata
and
Candida krusei
).The biological activity of two compounds was found to be
comparable to that of the commercially available fungicides (
6 and
9).
