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Journal of Postgraduate Medicine
Medknow Publications and Staff Society of Seth GS Medical College and KEM Hospital, Mumbai, India
ISSN: 0022-3859
EISSN: 0022-3859
Vol. 46, No. 4, 2000, pp. 278-279
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Bioline Code: jp00093
Full paper language: English
Document type: Research Article
Document available free of charge
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Journal of Postgraduate Medicine, Vol. 46, No. 4, 2000, pp. 278-279
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Case Report - Cerebellar Atrophy in an Epileptic Child: Is it Due to Phenytoin?
Ahuja SR, Karande S, Kulkarni MV
Abstract
A four and half year old epileptic child on phenytoin therapy since one year presented with signs of cerebellar dysfunction. Serum phenytoin level was high (33 mcg/ml) and computerised tomographic scan of the brain showed severe generalised cerebellar atrophy. The cerebellar signs represented drug overdosage and toxicity and persisted long after omission of phenytoin.
Keywords
Epilepsy, Cerebellum, Phenytoin
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