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Journal of Postgraduate Medicine
Medknow Publications and Staff Society of Seth GS Medical College and KEM Hospital, Mumbai, India
ISSN: 0022-3859 EISSN: 0022-3859
Vol. 51, No. 2, 2005, pp. 119-121
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Bioline Code: jp05047
Full paper language: English
Document type: Research Article
Document available free of charge
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Journal of Postgraduate Medicine, Vol. 51, No. 2, 2005, pp. 119-121
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Case Report - Accumulation of Tc99m-DMSA-3 in the spleen in a case of multiple myeloma with associated amyloidosis
Barai Sukanta, Bandopadhayaya G.P., Rathi M., Singh N.G.
Abstract
We describe a case of a 58-year-old male with longstanding hypertension and Type 2 diabetes mellitus who developed sudden onset renal impairment. The first clue to the possible presence of amyloidosis in this case was provided by the radionuclide renal cortical scan performed with trivalent dimercapto succinic acid (Tc99m-DMSA-3), which revealed intense tracer uptake in the spleen suggesting amyloid deposit. Further workup to ascertain the cause of amyloidosis led to the diagnosis of multiple myeloma. We conclude that in cases of extra-renal or splenic accumulation of Tc99m-DMSA-3, a diagnosis of amyloidosis should be considered, in an appropriate clinical setting.
Keywords
Amyloidosis, DMSA-3, multiple myeloma, spleen
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