The fruit bodies of three Ganoderma species namely
G. lucidium
,
G. applanatum
and
G. australe
were collected
from the decaying logs within the University of Ibadan Botanical Gardens .Invitro antagonistic effect of the ethanol, methanol
and distilled water extracts of these macro fungi were tested against some disease causing microorganisms. Both crude and
pure extracts of these
Ganoderma species exhibited various degree of inhibition against the test organisms. The widest
inhibitory zone (20.3mm) were obtained with the crude methanolic extract of
G. lucidium against
Proteus mirabilis
while the
highest in-vitro antifungal activity (24.3mm) was observed in the crude ethanolic extracts of
G. lucidium against
Aspergillus
niger
. The lowest zone of inhibition (2.3mm) was demonstrated with the aqueous extract of
G. australe against
Escherichia
coli
and 2.7mm with purified extract of
G. australe against
Penicillum oxalium
. The minimum inhibitory concentration (MIC)
for the ethanol extract ranged between 1.7 and 5.0mg/ml for bacteria and between 2.0 and 6.0mg/ml for fungi. The implications
of these findings were discussed.
