Plasma transfusion on the day of oocyte aspiration may reduce ovarian hyperstimulation syndrome in patients with polycystic ovary

Objective: To determine the efficiency of plasma transfusion on the day of oocyte aspiration in preventing ovarian hyperstimulation syndrome (OHSS) in polycystic ovary (PCO) patients undergoing ART cycles.
Design: Prospective randomized study.
Setting: The ART center at Alhelou International Hospital, Gaza city, Palestine.
Subjects: 93 PCO patients who are at risk of OHSS.
Intervention: 1-3 units of plasma were administrated on the day of oocyte aspiration.
Main Outcome Measures: The incidence and degrees of OHSS.
Results: 93 cases were randomized in total, 46 cases received plasma, 47 cases did not receive plasma (control). There was a noticeable difference in the two groups related to the occurrence of OHSS, the plasma group had 4 mild 8.7% and 1 moderate 2.2%, total % 10.9, where as 7 mild 14.9% and 3 moderate 6.4%, total % 21.3 in the control group, all were early onset of OHSS.
Conclusion: Our study proposes that plasma administration may reduce the percent and degree of OHSS in PCO patients undergoing ART. Plasma administration has no effect on the pregnancy rate.