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Malaysian Journal of Medical Sciences
School of Medical Sciences, Universiti Sains Malaysia
ISSN: 1394-195X
Vol. 22, No. 1, 2015, pp. 1-3
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Bioline Code: mj15001
Full paper language: English
Document type: Editorial
Document available free of charge
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Malaysian Journal of Medical Sciences, Vol. 22, No. 1, 2015, pp. 1-3
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What is Obesity Doing to Your Gut?
LEE, Yeong Yeh
Abstract
Obesity is a fast-emerging epidemic in the Asia-Pacific region, with numbers paralleling the rising global prevalence within the past 30 years. The landscape of gut diseases in Asia has been drastically changed by obesity. In addition to more non-specific abdominal symptoms, obesity is
the cause of gastro-oesophageal reflux disease, various gastrointestinal cancers (colorectal cancer, hepatocellular carcinoma, oesophageal adenocarcinoma, gastric cardia adenocarcinoma, pancreatic cancer and gallbladder cancer) and non-alcoholic fatty liver disease. Abnormal cross-talk between the gut microbiome and the obese host seems to play a central role in the pathogenesis, but more studies are needed.
Keywords
obesity; gastrointestinal tract; Asia-Pacific; microbiota; disease
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© Copyright 2015 - Malaysian Journal of Medical Sciences Alternative site location: http://www.medic.usm.my/publication/mjms/
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