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Neurology India
Medknow Publications on behalf of the Neurological Society of India
ISSN: 0028-3886 EISSN: 0028-3886
Vol. 52, No. 3, 2004, pp. 383-384
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Bioline Code: ni04124
Full paper language: English
Document type: Research Article
Document available free of charge
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Neurology India, Vol. 52, No. 3, 2004, pp. 383-384
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Short Report - Carcinomatous meningitis mimicking Creutzfeldt-Jakob disease
Vas CJ, Mallya MV, Desai M, Mahadevan A, Nadkarni NS, Shankar SK
Abstract
We report a case of carcinomatous meningitis diagnosed at autopsy that was clinically diagnosed as a case of Creutzfeldt-Jakob disease (CJD) because of rapidly evolving dementia. Pathological study revealed diffusely spreading carcinomatous meningitis, infiltrating into cortex along Virchow Robin space. Immunostaining for Prion protein was negative. Despite advances in clinical diagnosis, tissue diagnosis remains a pre-requisite for confirmation of CJD.
Keywords
Carcinomatous meningitis, CJD, Dementia
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