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Nigerian Journal of Physiological Sciences
Physiological Society of Nigeria
ISSN: 0794-859X
Vol. 29, No. 1, 2014, pp. 7-10
Bioline Code: np14002
Full paper language: English
Document type: Review Article
Document available free of charge

Nigerian Journal of Physiological Sciences, Vol. 29, No. 1, 2014, pp. 7-10

 en Vascular Effects of Histamine
Ebeigbe, Anthony B. & Talabi, Olufunke O.

Abstract

Four subtypes of receptors (H1, H2, H3 and H4) mediate the actions of histamine. In the vascular wall, the effects of histamine are mediated via H1 and H2 receptors and the actions are modulated by H3 receptor subtype located on presynaptic neurones. Alterations in vascular responses to histamine are associated with experimental as well as a human form of hypertension, suggesting a role for histanine in cardiovascular regulation.

Keywords
Histamine; Vascular smooth muscle; Endothelium

 
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