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Memórias do Instituto Oswaldo Cruz
Fundação Oswaldo Cruz, Fiocruz
ISSN: 1678-8060 EISSN: 1678-8060
Vol. 95, No. 1, 2000, pp. 115-120
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Bioline Code: oc00019
Full paper language: English
Document type: Research Article
Document available free of charge
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Memórias do Instituto Oswaldo Cruz, Vol. 95, No. 1, 2000, pp. 115-120
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Medicinal Products: Regulation of Biosynthesis in Space and Time
Otto R Gottlieb & Maria Renata de MB Borin
Abstract
We live in a "Demon-Haunted World". Human health care requires the ever increasing resistance of pathogens to be confronted by a correspondingly fast rate of discovery of novel antibiotics. One of the possible strategies towards this objective involves the rational localization of bioactive phytochemicals. The conceptual basis of the method consists in the surprisingly little known gearings of natural products with morphology, ecology and evolution of their plant source, i. e. an introspection into the general
mechanisms of nature.
Keywords
quantitative chemical biology - metabolism - morphology - ecology - evolution
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