Sm14 was the first fatty acid-binding protein homologue identified
in helminths. Thereafter, members of the same family were identified in
several helminth species, with high aminoacid sequence homology between
them. In addition, immune crossprotection was also reported against
Fasciola hepatica
infection, in animals previously immunized with the
Schistosoma mansoni
vaccine candidate, r-Sm14. In the present study, data on preliminary sodium
dodecyl sulphate-polyacrylamide gel electrophoresis and Western blotting
analysis of nine different helminth extracts focusing the identification
of Sm14 related proteins, is reported. Out of these, three extracts - Ascaris
suum (males and females),
Echinostoma paraensei
, and
Taenia saginata
- presented components that comigrated with Sm14 in SDS-PAGE, and that were
recognized by anti-rSm14 policlonal serum, in Western blotting tests.
