Twelve extracts obtained from nine plants belonging to six different genera of Clusiaceae were analyzed against Gram-negative (
Escherichia coli
and
Pseudomonas aeruginosa
) and Gram-positive (
Staphylococcus aureus
and
Enterococcus faecalis
) bacteria using the microdilution broth assay.
Tovomita aff.
longifolia, T. brasiliensis,
Clusia columnaris
,
Garcinia madruno
,
Haploclathra paniculata
, and
Caraipa grandifolia
extracts showed significant results against the bacteria. The organic extract obtained from the leaves of
T. aff. longifolia showed minimal inhibitory concentration (MIC) = 70 μg/ml and minimal bactericidal concentration (MBC) = 90 μg/ml against E. faecalis and the organic extract made with the stem of
C. columnaris showed MIC = 180 μg/ml and MBC = 270 μg/ml against
P. aeruginosa. None of the antibacterial extracts showed lethal activity against brine shrimp nauplii. On the other hand, both aqueous and organic extracts obtained from the aerial organs of
Vismia guianensis
that were cytotoxic to brine shrimp nauplii did not show a significant antibacterial activity in the assay.
