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Prevalence and Pattern of Congenital Heart Disease among Neonates in Gorgan, Northern Iran (2007-2008)
Nikyar, Bagher; Sedehi, Maliheh; Mirfazeli1, Arezo; Qorbani, Mostafa & Golalipour, Mohammad-Jafar
Abstract
Objective: Congenital heart disease (CHD) is the most common congenital anomaly in
newborns. The aim of this longitudinal, hospital-based study was to evaluate the prevalence
and pattern of CHD among Iranian newborns in Gorgan, Northern Iran.
Methods: 11739 live births in Dezyani hospital in Gorgan were screened for CHD, 2007 through
2008. Clinical examination, echocardiography, color Doppler and cardio catheterization were
used as diagnostic tools. Clinical and demographic factors, namely sex, type of CHD and
associated anomalies of diagnosed cases were recorded in a pre-designed questionnaire for
analysis.
Findings: The overall prevalence rate of CHD was 8.6 per 1000 live births. This was 9.96 per
1000 male births and 7.34 per 1000 female births. It was 4.5 and 13.19 per 1000 in 2007 and
2008, respectively. ASD was the commonest lesion (2.64 per 1000), followed by VSD+ASD (1.28
per 1000) and PDA (1.28 per 1000). The rate of ASD in male and female was 3.02 and 2.26 per
1000 respectively. Parents of 40 (39.6%) babies were related. 39 (38.6%) couples were first
cousins.
Conclusion: This study showed that the prevalence of CHD among live births in Gorgan is lower
than reported in the studies for Middle East and European countries.
Keywords
Congenital Heart Disease; Prevalence; ASD; VSD; Gender; Iran
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