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Iranian Journal of Pediatrics
Tehran University of Medical Sciences Press
ISSN: 1018-4406
EISSN: 1018-4406
Vol. 21, No. 4, 2011, pp. 543-548
Bioline Code: pe11094
Full paper language: English
Document type: Case Report
Document available free of charge

Iranian Journal of Pediatrics, Vol. 21, No. 4, 2011, pp. 543-548

 en Abdominal Inflammatory Myofibroblastic Tumor: Report on Four Cases and Review of Literature
Mirshemirani, Alireza; Tabari, Ahmad Khaleghnejad; Sadeghian, Naser; Shariat-Torbaghan, Siamak; Pourafkari, Marina & Mohajerzadeh, Leila


Background:The Abdominal Inflammatory Myofibroblastic Tumor (AIMT) is a rare tumor with unknown etiology which usually occurs in children and adolescents. It is composed of myofibroblastic spindle cells intermixed with inflammatory cells. We present four cases of AIMT.
Cases Presentation: We herein present four cases of AIMT in different ages (range: 3.5 to 13 years) and in different organs (stomach, periduodenal, mesenteric, and colon). There were two females and two males. The main symptoms were abdominal pain/mass/obstruction, vomiting, and weight loss. In all four patients, diagnosis was made by laparatomy and pathologic examination of excised mass lesion. Three patients underwent complete excision and no residual disease was present, one patient received chemotherapy due to tumor recurrences. The patients were followed up in average for four years.
Conclusion: As the imaging and laboratory tests are non-specific, the diagnosis of AIMT is rarely made before surgery. AIMT should, therefore, be considered when a mass arises in an unusual location in the pediatric age group. Complete surgical resection should be performed whenever possible and the child should be kept on long-term follow-up.

Inflammatory myofibroblastic tumor; Malignancy; Abdomen; Stomach; Duodenum; Mesenteric; Colon

© Copyright 2011 Iran Journal of Pediatrics
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