Iranian Journal of Pediatrics
Tehran University of Medical Sciences Press
Vol. 26, No. 3, 2016, pp. 101-104
Bioline Code: pe16043
Full paper language: English
Document type: Case Report
Document available free of charge
Iranian Journal of Pediatrics, Vol. 26, No. 3, 2016, pp. 101-104
© Copyright - 2016 Iranian Journal of Pediatrics
Fournier’s Gangrene in a Neonate With Acute Myeloid Leukemia: A Case Report|
Mosayebi, Ziba; Omidian, Ali; Movahedian, Amir Hossein; Kompani, Farzad & Hosseininodeh, Seyyed Saeed
Introduction: Fournier’s gangrene is an infective necrotizing fasciitis of external genital and perineal region. Hematologic malignancies
and immunocompromised status are predisposing factors. Simultaneous occurrence of Fournier’s gangrene and congenital
leukemia in neonates is extremely rare.
Case Presentation: We present a case of Fournier’s gangrene in a 4-day-old female infant with a necrotic lesion in perineum and
no history of trauma or other predisposing condition. Focusing on high blast percentage in blood cell count she was affected by
acute myeloid leukemia (M4 type). Pseudomonas aeruginosa was isolated from the blood and wound culture. She was treated with
broad spectrum antibiotics and supportive care. The parents refused chemotherapy and the patient was discharged from hospital.
Bleeding and DIC was the cause of death in a local hospital few days later.
Conclusions: High index of suspicion is essential for diagnosis and appropriate treatment. Congenital leukemia should be considered
in the differential diagnosis of a newborn with clinical features of sepsis and necrotizing fasciitis.
Fournier’s Gangrene; Acute Myeloid Leukemia; Neonate
Alternative site location: http://diglib.tums.ac.ir/pub/