![](/imgs/covers/ph_cover.jpg)
|
Indian Journal of Pharmacology
Medknow Publications on behalf of Indian Pharmacological Society
ISSN: 0253-7613 EISSN: 0253-7613
Vol. 38, No. 4, 2006, pp. 231-237
|
Bioline Code: ph06065
Full paper language: English
Document type: Research Article
Document available free of charge
|
|
Indian Journal of Pharmacology, Vol. 38, No. 4, 2006, pp. 231-237
en |
Educational Forum-Glucagon like peptide-1: A new therapeutic target for diabetes mellitus
Patel SK, Goyal RK, Anand IS, Shah JS, Patel HU, Patel CN
Abstract
Glucagon-like peptide-1 (GLP-1) is an endogenous peptide secreted from the gut in response to the presence of food. GLP-1 and its longer acting analog exendin-4 have multiple synergistic effects on glucose dependent, insulin secretion pathways of the pancreatic β-cell and on plasticity in neuronal cells. Recently the development of these peptides as a novel therapeutic strategy for non-insulin-dependent (type 2) diabetes mellitus and associated neuropathy has been the focus of much interest. Here we describe the biological actions of GLP-1 and its related analogs.
Keywords
Exendin-4, NIDDM
|
|
© Copyright 2006 Indian Journal of Pharmacology. Alternative site location: http://www.ijp-online.com
|
|