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Indian Journal of Pharmacology
Medknow Publications on behalf of Indian Pharmacological Society
ISSN: 0253-7613 EISSN: 0253-7613
Vol. 42, No. 6, 2010, pp. 334-337
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Bioline Code: ph10100
Full paper language: English
Document type: Symposium
Document available free of charge
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Indian Journal of Pharmacology, Vol. 42, No. 6, 2010, pp. 334-337
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Role of coenzyme Q10 as an antioxidant and bioenergizer in periodontal diseases
Prakash, Shobha; Sunitha, J. & Hans, Mayank
Abstract
Periodontal disease is an inflammatory disease process resulting from the interaction of a bacterial attack and host inflammatory response. Arrays of molecules are considered to mediate the inflammatory response at one time or another, among these are free radicals and reactive oxygen species (ROS). Periodontal pathogens can induce ROS overproduction and thus may cause collagen and periodontal cell breakdown. When ROS are scavenged by antioxidants, there can be a reduction of collagen degradation. Ubiquinol (reduced form coenzyme Q10) serves as an endogenous antioxidant which increases the concentration of CoQ10 in the diseased gingiva and effectively suppresses advanced periodontal inflammation.
Keywords
Antioxidant, bioenergizer, coenzyme Q10, periodontal disease
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© Copyright 2010 Indian Journal of Pharmacology. Alternative site location: http://www.ijp-online.com
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