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Tropical Journal of Pharmaceutical Research
Pharmacotherapy Group, Faculty of Pharmacy, University of Benin, Benin City, Nigeria
ISSN: 1596-5996 EISSN: 1596-5996
Vol. 11, No. 4, 2012, pp. 651-655
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Bioline Code: pr12077
Full paper language: English
Document type: Research Article
Document available free of charge
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Tropical Journal of Pharmaceutical Research, Vol. 11, No. 4, 2012, pp. 651-655
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Health-Related Quality of Life (HRQoL) in Co-Morbid Tuberculosis Relapse Patient: A Case Report from Malaysia
Atif, M; Sulaiman, SAS; Shafie, AA; Muttalif, AR; Hassali, MA & Saleem, F
Abstract
Purpose: To describe changes in HRQoL of pulmonary tuberculosis (PTB) patient and illustrate impact
of malnutrition and Type II diabetes on relapse of PTB.
Case: A Chinese male patient with complaints of productive cough, and loss of weight and appetite was
registered; sputum smear confirmed that patient had PTB. Diagnosis was also supported by routine
investigations. Patient had past history of PTB and Type II diabetes mellitus. For management of
secondary tuberculosis, he was prescribed WHO recommended therapy. Elevated HbA1c levels and
history of drop-off serum albumin concentration at the start of treatment demonstrated inappropriate
glycaemic control and malnutrition over the past months. SF-36v2 was used to estimate HRQoL scores
at start, after two months and at the end of TB therapy. Although patient's perception of mental and
physical health improved with progress of treatment, vitality (VT), social functioning (SF) and role
emotion (RE) scores were still lower than Malaysian norms. Patient was declared ‘cured’ but state of
‘health’ as defined by WHO was not achieved.
Conclusion: Relapse of PTB might be a consequence of inappropriate glycaemic control and
malnutrition. This case report demonstrates the need for more comprehensive efforts at TB programs to
improve HRQoL of TB patients.
Keywords
Related Quality of Life, Pulmonary tuberculosis, Malnutrition, Type II diabetes, SF 36v2
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