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Tropical Journal of Pharmaceutical Research
Pharmacotherapy Group, Faculty of Pharmacy, University of Benin, Benin City, Nigeria
ISSN: 1596-5996 EISSN: 1596-5996
Vol. 11, No. 4, 2012, pp. 657-664
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Bioline Code: pr12078
Full paper language: English
Document type: Research Article
Document available free of charge
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Tropical Journal of Pharmaceutical Research, Vol. 11, No. 4, 2012, pp. 657-664
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Adherence to Surgical Site Infection Guidelines in Cardiac Surgery in a Tertiary Hospital in Dubai, United Arab Emirates
Abu-Gharbieh, Eman & Fahmy, Sahar
Abstract
Purpose: To assess the appropriateness and compliance of antibiotic prophylaxis practices in cardiac
surgery in a tertiary hospital in United Arab Emirates (UAE) using three international guidelines.
Methods: A retrospective study was performed by reviewing patients' files admitted for cardiac surgery
between January 2008 and February 2010. The study evaluated the adherence of health care
professionals to three international guidelines with regard to antibiotic prophylaxis. The guidelines were
National Surgical Infection Prevention Project (NSIPP), Society of Thoracic Surgeons (STS) and
American College of Cardiology/American Heart Association (ACC/AHA). Patients’ records were
reviewed for antibiotics used for prophylaxis, frequency of administration, timing and number of doses.
Results: A total of 92 patients were included in the study. Based on the international guidelines, only
89.1 and 79.3% of the patients received the recommended pre- and post-operative antibiotics,
respectively. On the other hand, 93.5% of the patients received the right antibiotic dose while the total
duration of all antimicrobial agents used for prophylaxis was concordant with the guidelines (48 h) in
only 67.4% of the patients.
Conclusion: Adherence to international antimicrobial prophylaxis guidelines for cardiac surgery was
found to be suboptimal in the study hospital in Dubai. Various interventions are needed via developing
local evidence-based protocols in collaboration with surgeons, and also to strengthen regulations for
ensuring adherence to these guidelines.
Keywords
Antimicrobial prophylaxis, International guidelines, Cardiac surgery
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