Purpose; Hunteria umbellata
has been found to have therapeutic potentials in the treatments of
diseases such as yaws, peptic ulcers, diabetes, piles and infertility in Nigeria; hence, the statistical
analysis on the determination of acute toxicity of
Hunteria umbellata was carried out in mice.
Methods; Data on the acute toxicity studies of the seed extract of
Hunteria umbellata administered via
the intraperitoneal route was analyzed using the two-parameter Weibull model.
Results; The median lethal dose (LD
50) was 1.61 g/kg of body weight. This result falls in the
neighbourhood of the median lethal dose earlier obtained in previous reports.
Conclusion;The results show that
Hunteria umbellata may be slightly toxic when administered
intraperitoneally.
