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Tropical Journal of Pharmaceutical Research
Pharmacotherapy Group, Faculty of Pharmacy, University of Benin, Benin City, Nigeria
ISSN: 1596-5996 EISSN: 1596-5996
Vol. 11, No. 6, 2012, pp. 1001-1011
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Bioline Code: pr12119
Full paper language: English
Document type: Review Article
Document available free of charge
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Tropical Journal of Pharmaceutical Research, Vol. 11, No. 6, 2012, pp. 1001-1011
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Impact of Nanoparticles on Cancer Therapy
Alkhatib, Mayson H; Albishi, Hayat M & Mahassni, Sawsan H
Abstract
The tremendous contribution of nanotechnology to the treatment and diagnosis of medical diseases has
recently attracted the attention of anticancer researchers. Most of the new nanoparticle carriers have
improved drug bioavailability and reduced the cytotoxic effects of the drugs. This article presents an
overview of the recent advances of nanotechnology in cancer therapy. It covers the mechanisms of
cellular uptake for anticancer drugs delivered in nanoscale systems by either active or passive targeting.
The various nanoscale systems employed in drug delivery and their immense potential in diagnosis and
imaging of cancerous tumors are also addressed.
Keywords
Nanocarriers, Drug delivery, Liposomes, Micelles, Dendrimers, Emulsification systems
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