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Tropical Journal of Pharmaceutical Research
Pharmacotherapy Group, Faculty of Pharmacy, University of Benin, Benin City, Nigeria
ISSN: 1596-5996 EISSN: 1596-5996
Vol. 12, No. 5, 2013, pp. 777-782
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Bioline Code: pr13097
Full paper language: English
Document type: Research Article
Document available free of charge
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Tropical Journal of Pharmaceutical Research, Vol. 12, No. 5, 2013, pp. 777-782
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Preliminary Phytochemical and Physicochemical Characterization of Gynura segetum (Lour) Merr (Compositae) Leaf
Seow, Lay Jing; Beh, Hooi Kheng; Sadikun, Amirin & Asmawi, Mohd Zaini
Abstract
Purpose: To carry out phytochemical and physicochemical studies on the leaves of Gynura segetum.
Methods: Preliminary phytochemical and physicochemical studies using chromatographic techniques,were carried out, Parameters evaluated include ash value, loss on drying and extractive value, amongst others. .
Results: Phytochemical results revealed that the leaves of Gynura segetum contain alkaloid, terpene, flavonoid, tannin and saponin. Mean ash value (%) was 13.5 (total), 2.49 (acid-insoluble ash) and 6.14 (water-soluble ash). Loss on drying was 10.70 % while extractive value was 20.60 % in water and 14.13 % in ethanol. Thin layer chromatography (TLC) analysis indicates the presence of rutin in the methanol extract of G. segetum and this was supported by high performance liquid chromatography (HPLC) studies.
Conclusion: Useful quantitative and descriptive data essential for identifying and characterizing the plant for the purpose of quality control are presented.
Keywords
Gynura segetum; Quality control; Extractive; Ash value
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