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Tropical Journal of Pharmaceutical Research
Pharmacotherapy Group, Faculty of Pharmacy, University of Benin, Benin City, Nigeria
ISSN: 1596-5996 EISSN: 1596-5996
Vol. 15, No. 4, 2016, pp. 869-876
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Bioline Code: pr16117
Full paper language: English
Document type: Research Article
Document available free of charge
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Tropical Journal of Pharmaceutical Research, Vol. 15, No. 4, 2016, pp. 869-876
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Erectile dysfunction: prevalence, risk factors and involvement of antihypertensive drugs intervention
Salman, Muhammad; Shehzadi, Naureen; Khan, Muhammad T.; Islam, Muhammad; Khan, Amer H. & Hussain, Khalid
Abstract
Purpose:
To explore the literature regarding prevalance, risk factors and the involvement of
antihypertensive drugs in erectile dysfunction (ED).
Methods:
Original research articles, reviews, editorials and case reports published in English language
on the prevalence of sexual/erectile dysfunction in hypertensive men taking antihypertensive drugs and
risk factors were identified through a search of four bibliographic databases, namely, PubMed,
EMBASE, CINAHL and EBSCO Health.
Results:
Recent analyses suggest that hypertensive men of almost all age groups suffer from ED but it
is more prevalent in elderly male patients. The involvement of β-blockers was found to be controversial.
Nevertheless, some evidence had been found regarding the use of propranolol in high doses.
Conclusion:
The present review indicates the need for research to unravel the role of β-blockers in the
manifestation of ED in hypertensive males, whom there are no contributory factors such as sedentary
lifestyle, aging, stress and anxiety, etc.
Keywords
Hypertension; Antihypertensive drugs; β-Blockers; Erectile dysfunction; Propranolol; Life styleRisk factors
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