search
for
 About Bioline  All Journals  Testimonials  Membership  News


Iranian Journal of Pharmacology and Therapeutics
Razi Institute for Drug Research (RIDR) of Iran University of Medical Sciences and Health Services (IUMS)
ISSN: 1735-2657
Vol. 4, No. 1, 2005, pp. 24-27 		Bioline Code: pt05006
Full paper language: English
Document type: Research Article
Document available free of charge

Iranian Journal of Pharmacology and Therapeutics, Vol. 4, No. 1, 2005, pp. 24-27

 en Antidiarrheal Evaluation of Benincasa hispida   check for this species in other resources (Thunb.) Cogn. Fruit Extracts
VRUSHABENDRA SWAMY BHYRAPUR MATHAD, SRIDHAR CHANDANAM, SREENIVASA RAO THIRUMALA SETTY, DHANAPAL RAMAIYAN, BALAMURALIDHAR VEERANNA, ASHOKA BABU VECHHAM LAKSHMINARAYANASETTRY

Abstract

The methanolic extract of fruit of Benincasa hispida   check for this species in other resources (BHFE) was evaluated for its antidiarrheal potential against several experimental models of diarrhea in rats. BHFE treated animals showed significant inhibitory activity against castor oil induced diarrhea and inhibited PGE2 induced enter pooling in rats. It also showed significant reduction in gastro intestinal motility following charcoal meal in rats. The result obtained and establishes the efficacy of BHFE as an antidiarrheal agent.

Keywords
Benicasa hispida, Antidiarrheal, Fruits, BHFE

 
© Copyright 2005 - Razi Institute for Drug Research (RIDR)
Alternative site location: http://ijpt.iums.ac.ir/

Home Faq Resources Email Bioline
© Bioline International, 1989 - 2024, Site last up-dated on 01-Sep-2022.
Site created and maintained by the Reference Center on Environmental Information, CRIA, Brazil
System hosted by the Google Cloud Platform, GCP, Brazil