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Iranian Journal of Pharmacology and Therapeutics
Razi Institute for Drug Research (RIDR) of Iran University of Medical Sciences and Health Services (IUMS)
ISSN: 1735-2657
Vol. 4, No. 2, 2005, pp. 72-75
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Bioline Code: pt05016
Full paper language: English
Document type: Research Article
Document available free of charge
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Iranian Journal of Pharmacology and Therapeutics, Vol. 4, No. 2, 2005, pp. 72-75
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Sildenafil Determination in Various Matrices: A Review
MASSOUD MAHMOUDIAN
Abstract
Determination of sildenafil by various methods and in various media is reviewed in this paper. The meth-ods used consist of ultraviolet (UV) spectroscopy, thin layer chromatography (TLC), and high-performance liquid chromatography (HPLC). These methods were used to determine the amount of sil-denafil in pharmaceutical preparations, soft drinks, and biological liquids. HPLC was used for evaluation of pharmacokinetic parameters of sildenafil. It is concluded that HPLC is the most reliable and applicable method in this regard.
Keywords
Sildenafil, HPLC, pharmaceutical preparations, soft drinks, biological liquids
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© Copyright 2005 - Razi Institute for Drug Research (RIDR)
Alternative site location: http://ijpt.iums.ac.ir/
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