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International Journal of Reproductive BioMedicine
Research and Clinical Center for Infertility, Shahid Sadoughi University of Medical Sciences of Yazd
ISSN: 1680-6433 EISSN: 1680-6433
Vol. 15, No. 5, 2017, pp. 257-264
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Bioline Code: rm17035
Full paper language: English
Document type: Review Article
Document available free of charge
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International Journal of Reproductive BioMedicine, Vol. 15, No. 5, 2017, pp. 257-264
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Revealing the secret life of pre-implantation embryos by time-lapse monitoring: A review
Faramarzi, Azita; Khalili, Mohammad Ali; Micara, Giulietta & Agha-Rahimi, Azam
Abstract
High implantation success following in vitro fertilization cycles are achieved via the
transfer of embryos with the highest developmental competence. Multiple
pregnancies as a result of the transfer of several embryos per cycle accompany with
various complication. Thus, single-embryo transfer (SET) is the preferred practice in
assisted reproductive technique (ART) treatment. In order to improve the pregnancy
rate for SET, embryologists need reliable biomarkers to aid their selection of
embryos with the highest developmental potential. Time-lapse technology is a
noninvasive alternative conventional microscopic assessment. It provides
uninterrupted and continues the survey of embryo development to transfer day.
Today, there are four time-lapse systems that are commercially available for ART
centers. In world and Iran, the first time lapse babies were born in 2010 and 2015,
respectively, conceived by SET. Here, we review the use of time-lapse monitoring in
the observation of embryogenesis as well as its role in SET. Although, the findings
from our review support common use of time-lapse monitoring in ART centers; but,
future large studies assessing this system in well-designed trials are necessary.
Keywords
Embryo selection; Kinetic; Assisted reproductive technology; Time-lapse.
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© Copyright 2017 - International Journal of Reproductive Medicine Alternative site location: http://www.ijrm.ir
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