Antimicrobial resistance in developing countries has long been an issue of major concern. Nanotechnology has
become an eye opener for the intervention on multiple drug resistance organisms. In this study we investigated the
antimicrobial potentials of Silver Nitrate (nanorods) solution used in managing infectious diseases, the Minimum Inhibitory
Concentration (MIC) and Minimum Bactericidal Concentration (MBC) of the product against microbial isolates were
determined using standard microbiological techniques. The mean MIC and MBC of silver nitrate solution on fungi (0.16
μg/ml and 0.29 μg/ml respectively) was significantly lower than that of Gram positive organisms (2.35μg/ml and 2.62μg/ml)
and Gram negative organisms (2.05 μg/ml and 2.10 μg/ml). Of all the Gram positive organisms,
Staphylococcus spp
recorded
the lowest mean MICand MBC while in the Gram negative organisms group,
E. coli
isolates showed the lowest mean MIC
and MBC of the silver nitrate solution, though not significantly different from the other isolates. In conclusion, results from
this study revealed that Silver Nitrate(nanorods) may have be broad spectrum in activity, but with higher antifungal
potentials.
