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Journal of Cancer Research and Therapeutics
Medknow Publications on behalf of the Association of Radiation Oncologists of India (AROI)
ISSN: 0973-1482 EISSN: 0973-1482
Vol. 6, No. 3, 2010, pp. 388-390
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Bioline Code: cr10097
Full paper language: English
Document type: Case Report
Document available free of charge
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Journal of Cancer Research and Therapeutics, Vol. 6, No. 3, 2010, pp. 388-390
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Neurofibroma of kidney: An uncommon neoplasm and diagnostic dilemma with solitary fibrous tumor
Mondal, Santosh Kumar; Mallick, Mamata Guha; Bandyopadhyay, Ranjana & Mondal, Palash Kumar
Abstract
Neurofibroma of kidney is an extremely rare tumor. To our knowledge, only five such cases have been reported worldwide till date. Here, we report a solitary neurofibroma of right kidney in a 54-year-old woman. Radiological investigations (ultrasonography and computed tomography) detected a solid mass in the upper pole of right kidney and clinicoradiologically renal cell carcinoma was suspected. A radical nephrectomy was performed under diagnosis of cancer. Microscopically, tumor consisted of benign spindle-shaped cells accompanied by fibrous tissue. Differential diagnoses of neurofibroma and solitary fibrous tumor (SFT) were made on morphological features. Immunohistochemically, the tumor cells were positive for S-100 protein, but negative for CD34 and CD99. Thus, a diagnosis of neurofibroma was established.
Keywords
Immunohistochemistry, kidney tumor, neurofibroma, spindle cells
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© Copyright 2010 Journal of Cancer Research and Therapeutics. Alternative site location: http://www.cancerjournal.net/
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