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Journal of Cancer Research and Therapeutics
Medknow Publications on behalf of the Association of Radiation Oncologists of India (AROI)
ISSN: 0973-1482 EISSN: 0973-1482
Vol. 7, No. 2, 2011, pp. 189-191
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Bioline Code: cr11044
Full paper language: English
Document type: Case Report
Document available free of charge
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Journal of Cancer Research and Therapeutics, Vol. 7, No. 2, 2011, pp. 189-191
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Cytology of hyalinising trabecular adenoma-like variant of medullary thyroid carcinoma
Santosh, K V.; Raychaudhuri, Sujata; Subramanya, H & Naveen Kumar, B J.
Abstract
Medullary thyroid carcinoma is a rare thyroid neoplasm that can be either sporadic or familial. It occurs in adults, presenting as a solitary cold nodule on thyroid scan. Most are solid, firm, and non-encapsulated, and occur in the mid portion or upper half of the thyroid gland, corresponding to areas with greater numbers of C cells. We present a case of a 36-year-old female with a swelling in the front of her neck for six years. Fine needle aspiration done elsewhere revealed spindle cells, suggestive of a ′spindle cell neoplasm′. The histopathology of the thyroidectomy specimen showed features of a hyalinizing trabecular adenoma-like variant of medullary carcinoma. Subsequently, we performed aspiration on the received specimen and studied the cytological findings. The cytological diagnosis of this variant requires identification of the dual spindle and ovoid cell population and the granular neuroendocrine chromatin.
Keywords
Fine needle aspiration cytology, hyalinizing trabecular, medullary carcinoma, thyroid
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© Copyright 2011 Journal of Cancer Research and Therapeutics. Alternative site location: http://www.cancerjournal.net/
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