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European Journal of General Medicine
Medical Investigations Society
ISSN: 1304-3897
Vol. 4, No. 4, 2007, pp. 190-198
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Bioline Code: gm07044
Full paper language: English
Document type: Case Report
Document available free of charge
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European Journal of General Medicine, Vol. 4, No. 4, 2007, pp. 190-198
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Antidiabetic Treatment In Diabetic Patients With Coronary Artery Disease
Soylu, Ahmet; Ülgen, Mehmet S. & Düzenli, Mehmet Akif
Abstract
The prevalence of diabetes mellitus (DM) that is about 150 million today is estimated to
exceed 300 million by the year 2025 (1). When considered that about half of the patients remain
undiagnosed, it can be seen how serious the dimensions of the disease are (2). In the patients with
DM more than 90% of whom are consisted by non-insulin dependent diabetes mellitus (NIDDM,
Type 2 DM), the disease is a significant risk factor for the development of coronary artery disease
(CAD) responsible for 75% of all deaths (3,4). In this group of the patients who generally require
antidiabetic treatment inevitably, it is highly important to decide on an appropriate treatment
due to the various cardiovascular (CV) effects of the anti-diabetics medications and drugs. In
order to help establish this decision, in this review it was tried to investigate antidiabetic drugs
after a general approach to CAD pathophysology in diabetic patients, especially in terms of their
cardiovascular effects.
Keywords
Antidiabetic treatment, coronary artery disease
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