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The Journal of Health, Population and Nutrition
icddr,b
ISSN: 1606-0997 EISSN: 1606-0997
Vol. 22, No. 4, 2004, pp. 440-442
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Bioline Code: hn04053
Full paper language: English
Document type: Report
Document available free of charge
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The Journal of Health, Population and Nutrition, Vol. 22, No. 4, 2004, pp. 440-442
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Zinc Therapy for Diarrhoea Increased the Use of Oral Rehydration Therapy and Reduced the Use of Antibiotics in Bangladeshi Children
Baqui, Abdullah H.; Black, Robert E.; El Arifeen, Shams; Yunus, Mohammad; Zaman, K.; Begum, Nazma; Roess, Amira A. & Santosham, Mathuram
Abstract
Excessive use of antibiotics for diarrhoea is a major contributing factor towards increasing rates of
antimicrobial resistance in developing countries. Zinc therapy for diarrhoea has been shown to be beneficial
in controlled efficacy trials, and it is of interest to determine if availability of zinc syrup for treatment
of diarrhoea would satisfy the demand for a 'medicine' for diarrhoea, thus reducing the use of
antibiotics, without competing with the use of oral rehydration therapy (ORT). This community-based
controlled trial was conducted from November 1998 to October 2000, and all children aged 3-59
months in the study area were included. In this trial, the availability of zinc supplements, along with
ORT and appropriate education programmes, was associated with significantly higher use of ORT and
lower use of antibiotics.
Keywords
Zinc; Zinc therapy; Diarrhoea; Infantile; Oral rehydration therapy; Antibiotics; Bangladesh
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