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African Health Sciences
Makerere University Medical School
ISSN: 1680-6905 EISSN: 1680-6905
Vol. 18, No. 4, 2018, pp. 1182-1188
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Bioline Code: hs18152
Full paper language: English
Document type: Study
Document available free of charge
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African Health Sciences, Vol. 18, No. 4, 2018, pp. 1182-1188
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Resistance status to deltamethrin pyrethroid of Culex pipiens pipiens (Diptera: Culicidae) collected from three districts of Tunisia
Tabbabi, Ahmed; Daaboub, Jabeur; Cheikh, Raja Ben; Laamari, Ali; Feriani, Mohamed; Boubaker, Chokri; Jha, Ibtissem Ben & Cheikh, Hassen Ben
Abstract
Objectives: The aim of the present study was to determine the susceptibility status of Culex pipiens pipiens populations against deltamehtrin insecticide.
Methods: Larvae of Culex pipiens pipiens were collected from three breeding places in Northern and Southern Tunisia between 2003 and 2005. Early third and late fourth instars were tested against deltamethrin pyrethroid insecticide. Cross-resistance with DDT resistance was evaluated in studied samples to estimate the role of target site insensitivity and two synergists including piperonyl butoxide (Pb) and S,S,S-tributyl phosphorotrithioate (DEF) were used to estimate the role of detoxification enzymes.
Results: Our results revealed that the level of deltamehtrin resistance ranged from 0.67 to 31.4. We also showed the non-involvement of kdr resistance in pyrethroid resistance and no cross-resistance with DDT resistance was detected in all studied populations including the most resistant one. Synergists study on the resistant population (sample # 1) showed the involvement of CYP450 in the recorded resistance to the deltamethrin insecticide.
Conclusion: The results obtained from this study should be considered in the current control programs to combat mosquitoes
in Tunisia.
Keywords
Culex pipiens pipiens; deltamethrin resistance; kdr mutation; detoxification; Tunisia
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© Copyright 2018 - Tabbabi et al.
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