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Journal of Postgraduate Medicine
Medknow Publications and Staff Society of Seth GS Medical College and KEM Hospital, Mumbai, India
ISSN: 0022-3859 EISSN: 0022-3859
Vol. 49, No. 2, 2003, pp. 141-147
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Bioline Code: jp03037
Full paper language: English
Document type: Research Article
Document available free of charge
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Journal of Postgraduate Medicine, Vol. 49, No. 2, 2003, pp. 141-147
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Special Article - Smallpox: Clinical Highlights and Considerations for Vaccination
Mahoney MC, Symons AB, Kimmel SR
Abstract
Smallpox virus has gained considerable attention as a potential bioterrorism agent. Recommendations for smallpox (vaccinia) vaccination presume a low risk for use of smallpox as a terrorist biological agent and vaccination is currently recommended for selected groups of individuals such as health care workers, public health authorities, and emergency/rescue workers, among others. Information about adverse reactions to the smallpox vaccine is based upon studies completed during the 1950s and 1960s. The prevalence of various diseases has changed over the last four decades and new disease entities have been described during this period. The smallpox vaccination may be contra-indicated in many of these conditions. This has made pre-screening of potential vaccines necessary. It is believed that at present, the risks of vaccine-associated complications far outweigh the potential benefits of vaccination in the general population. (J Postgrad Med 2003;49:141-147)
Keywords
Smallpox/epidemiology/history/physiopathology/prevention & control, smallpox vaccine/administration & dosage/adverse effects, biological warfare
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