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Journal of Postgraduate Medicine
Medknow Publications and Staff Society of Seth GS Medical College and KEM Hospital, Mumbai, India
ISSN: 0022-3859 EISSN: 0022-3859
Vol. 55, No. 1, 2009, pp. 22-26
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Bioline Code: jp09006
Full paper language: English
Document type: Research Article
Document available free of charge
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Journal of Postgraduate Medicine, Vol. 55, No. 1, 2009, pp. 22-26
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Comparison of Internal Sphincterotomy With Topical Diltiazem for Post-Hemorrhoidectomy Pain Relief: A Prospective Randomized Trial
Chauhan, A.; Tiwari, S.; Mishra, V.K. & Bhatia, P.K.
Abstract
Aim: To assess the efficacy of internal sphincterotomy compared with application of topical 2% Diltiazem ointment after hemorrhoidectomy for pain relief.
Settings and Design: Prospective randomized study.
Materials and Methods: In an 18-month period, 108 subjects with uncomplicated Grade 3/ 4 hemorrhoids were enrolled in the study and were randomized into two equal groups: Subjects in Group A underwent internal sphincterotomy at time of primary surgery while those in Group B received 1 g of 2% Diltiazem ointment locally, thrice daily for seven days. Postoperative pain perception was measured using visual analog score (VAS) and on the basis of number of analgesic tablets (Tab tramadol 50 mg) required in each group. Time to discharge, time to return to work and incidence of complications measured and compared.
Statistical Analysis Used: Statistical techniques applied were Student T test, Chi-square and Fisher′s Exact Test.
Results: There were 102 analyzable subjects (Group A: 50 and Group B: 52). The mean VAS score was significantly less in the internal sphincterotomy group from the fourth postoperative day onwards compared to topical Diltiazem (2.23 vs. 3.72; P =0.031). Similarly, the mean requirement of analgesic tablets [10.54 vs. 15.40; P =0.01] was much lower in Group A. There was no significant difference in terms of time to discharge and time to return to work between the two groups. The incidence of complications was more with the internal sphincterotomy group (11.5% vs. 3 %; P =0.488).
Conclusions: In patients undergoing hemorrhoidectomy, addition of surgical internal sphincterotomy results in lesser pain in the postoperative period as compared to those receiving topical application of Diltiazem.
Keywords
Chemical sphincterotomy, hemorrhoidectomy, internal sphincterotomy, pain relief, topical Diltiazem
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