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East and Central African Journal of Surgery
Association of Surgeons of East Africa and College of Surgeons of East Central and Southern Africa
ISSN: 1024-297X EISSN: 1024-297X
Vol. 22, No. 1, 2017, pp. 88-97
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Bioline Code: js17012
Full paper language: English
Document type: Research Article
Document available free of charge
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East and Central African Journal of Surgery, Vol. 22, No. 1, 2017, pp. 88-97
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A Cross Section Study to Correlate Fine Needle Aspiration Cytology and Histopathology in the Diagnosis of Parotid Tumours at Four Major Hospitals in Zambia
Kazuma, S. M. E.; Mucheleng’anga, L.; Zulu, R. & Hanna, H.
Abstract
Background: Needle Aspiration Cytology (FNAC) is cheap, simple, quick, minimally
invasive procedure that is widely used for preoperative diagnosis of Parotid tumours.
Methods: Twenty five patients were prospectively studied over a two-year period at four
major hospitals in Zambia. FNAC was done using a 10cc syringe and 20-22G needles for
sample collection and specimen staining was done with papanicolaou stain.
Histopathology was assessed with Haematoxylin and Eosin (H&E) stained sections.
Results: FNAC correlated with histopathology with a sensitivity of 100% and specificity of
66.7%; positive and negative predictive values of 95.7% and 100% respectively and a
likelihood ratio of 3. All Parotid tumours were neoplastic with 76% benign and 24%
malignant tumours on histopathology. FNAC accurately diagnosed 68% benign and 20%
malignant tumours.
Conclusion: This study found that FNAC correlates well with histopathology in the
diagnosis of parotid tumours. FNAC is useful in the preoperative assessment of Parotid
tumours as it provides a preoperative diagnosis that influences management by either
avoiding surgery (inflammatory lesion) and limiting the extent of surgery for benign and
malignant Parotid tumours.
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© Copyright 2017 - East and Central African Journal of Surgery
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