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Indian Journal of Medical Microbiology
Medknow Publications on behalf of Indian Association of Medical Microbiology
ISSN: 0255-0857 EISSN: 0255-0857
Vol. 25, No. 3, 2007, pp. 253-255
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Bioline Code: mb07070
Full paper language: English
Document type: Research Article
Document available free of charge
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Indian Journal of Medical Microbiology, Vol. 25, No. 3, 2007, pp. 253-255
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Circulating filarial antigen in serum and hydrocele fluid from individuals living in an endemic area for bancroftian filariasis
Shah, AP & Mulla, SA
Abstract
This study examined circulating filarial antigen by monoclonal antibody Og4C3-enzyme-linked immunosorbent assay (ELISA) from 114 men with hydrocele, living in an endemic area. Nocturnal blood and hydrocele fluid were collected and examined for microfilaria. ELISA was performed on serum and hydrocele fluid for detection of antigen. Amongst 114 cases, 5(4.4%) showed microfilaria in blood but none in fluid. ELISA was positive in 13(11.40%) serum and 5 (4.4%) fluid samples. All five fluid antigen positive cases were positive for antibodies and showed microfilaria in blood. These findings emphasize the use of circulating filarial antigen detection and alternative usage of hydrocele fluid for diagnosis of filariasis.
Keywords
Wuchereria bancrofti, Og4C3 antigen, hydrocele fluid, lymphatic filariasis
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© Copyright 2007 Indian Journal of Medical Microbiology. Alternative site location: http://www.ijmm.org
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