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Indian Journal of Medical Microbiology
Medknow Publications on behalf of Indian Association of Medical Microbiology
ISSN: 0255-0857 EISSN: 0255-0857
Vol. 26, No. 2, 2008, pp. 123-126
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Bioline Code: mb08037
Full paper language: English
Document type: Research Article
Document available free of charge
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Indian Journal of Medical Microbiology, Vol. 26, No. 2, 2008, pp. 123-126
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The highest prevalence of human metapneumovirus in Ahwaz children accompanied by acute respiratory infections
Arabpour, M; Samarbafzadeh, AR; Makvandi, M; Shamsizadeh, A; Percivalle, E; Englud, Janet & Latifi, Seid Mannut
Abstract
Purpose: The newly described human metapneumovirus (hMPV) has been recently discovered as an etiological agent of acute respiratory infections (ARTI) in infants and children. The aim of this study was to determine the prevalence of hMPV and its potential role as causative agent of ARTI in Ahwaz children. Methods: In the present study, we examined 124 nasal swabs from infants affected by ARTI for the presence of hMPV by RT-PCR technique. Results: Sixty-eight out of 124 (54.4%) cases were positive for hMPV which is the highest incidence of hMPV ever reported in the world, 94.1% of positive cases belonged to genotype A; whereas no B genotype was detected. Our positive hMPV children were affected by upper (URTI) as well as lower respiratory tract infection (LRTI); however, LARTIs had higher prevalence. Conclusions: We suggest a probable role of F protein alteration as the causative agent for the highest prevalence of hMPV infection among Ahvaz children.
Keywords
Ahwaz, acute respiratory infections, human metapneumovirus
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© Copyright 2008 Indian Journal of Medical Microbiology. Alternative site location: http://www.ijmm.org
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