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Indian Journal of Medical Microbiology
Medknow Publications on behalf of Indian Association of Medical Microbiology
ISSN: 0255-0857 EISSN: 0255-0857
Vol. 29, No. 2, 2011, pp. 178-180
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Bioline Code: mb11041
Full paper language: English
Document type: Case Report
Document available free of charge
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Indian Journal of Medical Microbiology, Vol. 29, No. 2, 2011, pp. 178-180
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Fatal rabies despite post-exposure prophylaxis
Deshmukh, D. G.; Damle, A. S.; Bajaj, J. K.; Bhakre, J. B. & Patil, N. S.
Abstract
Only sporadic reports of failure of post-exposure prophylaxis for rabies exist in the published literature. We are reporting such a case in a 3-year-old boy. The child had Category III dog bite on his right thigh. He presented with progressive ascending paralysis, finally developing quadriplegia and respiratory paralysis. Typical hydrophobia and aerophobia were absent. He received four doses of antirabies cell culture vaccine. He did not receive antirabies immunoglobulin. The boy succumbed on the 23 rd day of the dog bite. Diagnosis of rabies was confirmed in the laboratory by demonstration of Negri bodies, direct fluorescent antibody test and reverse transcriptase-polymerase chain reaction either on impression smear of brain or a piece of brain taken during autopsy.
Keywords
Post-exposure prophylaxis, rabies
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© Copyright 2011 Indian Journal of Medical Microbiology. Alternative site location: http://www.ijmm.org
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