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Malaysian Journal of Medical Sciences
School of Medical Sciences, Universiti Sains Malaysia
ISSN: 1394-195X
Vol. 16, No. 1, 2009, pp. 25-33
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Bioline Code: mj09004
Full paper language: English
Document type: Short Communication
Document available free of charge
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Malaysian Journal of Medical Sciences, Vol. 16, No. 1, 2009, pp. 25-33
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Radioiodine I-131 For The Therapy Of Graves’ Disease
Mumtaz, Malik; Lin, Lim Shueh; Hui, Khaw Chong & Khir, Amir Sharifuddin Mohd
Abstract
Graves’ disease is a common cause of hyperthyroidism. Treatment options for Graves’ disease
include antithyroid medication, surgery or radioactive iodine (I-31) or RAI. This review will focus on
the approach to RAI therapy; discussing dose selection, patient preparation, and consideration before
and after administering RAI, examining aspects of pre-treatment with antithyroid medication as well
as discussing possible adverse events including hypothyroidism and possible worsening of thyroidassociated
opthalmopathy. Follow-up is lifelong with the aim of ensuring the patient remains euthyroid
or on replacement therapy if there is evidence of hypothyroidism. While there are controversies
in treatment of thyrotoxicosis with RAI, with appropriate patient selection and regular follow-up,
radioiodine is a safe and effective modality in achieving high cure rates.
Keywords
radioactive iodine, Graves’ disease, thyroid, treatment, medical sciences
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© Copyright 2009 - Malaysian Journal of Medical Science Alternative site location: http://www.medic.usm.my/publication/mjms/
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