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Brazilian Journal of Oral Sciences
Piracicaba Dental School - UNICAMP
EISSN:
Vol. 8, No. 3, 2009, pp. 114-118
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Bioline Code: os09023
Full paper language: English
Document type: Review Article
Document available free of charge
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Brazilian Journal of Oral Sciences, Vol. 8, No. 3, 2009, pp. 114-118
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Clinical trials with nanoparticle composite in posterior teeth: a systematic literature review
Andrade, Ana Karina Maciel; Duarte, Rosângela Marques; Medeiros e Silva, Fábia Danielle Sales da Cunha; Batista, André Ulisses Dantas; Lima, Kenio Costa & Montes, Marcos Antonio Japiassú Resende
Abstract
Aim:
The aim of this article is to evaluate clinical trials with nanoparticle composite in posterior teeth through
a systematic review of the literature.
Methods:
This analysis includes controlled clinical trials with
nanoparticle composites, with at least 6 months of evaluation, published in the English language between
1997 and 2009. In vitro and retrospective studies and studies on anterior teeth were excluded. Articles were
retrieved from the following full-text electronic journal databases: MEDLINE, LILACS and The Cochrane
Library.
Results:
The largest number of articles was found in the MEDLINE database, but only 4 of them
met the inclusion and exclusion criteria. No articles were found in the LILACS database; only two articles
were selected from The Cochrane Library databases and they coincided with those already included in
MEDLINE.
Conclusions:
The nanoparticle composites give a satisfactory performance for use in posterior
teeth for at least 2 years of functional activity, but their performance was not superior to that of the other
composites. Long-term studies must be conducted to evaluate the performance after 2 years of functional
activity. New controlled and randomized clinical trials are necessary.
Keywords
controlled clinical trials, composite resins
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