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Indian Journal of Pharmacology
Medknow Publications on behalf of Indian Pharmacological Society
ISSN: 0253-7613 EISSN: 0253-7613
Vol. 42, No. 4, 2010, pp. 245-246
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Bioline Code: ph10070
Full paper language: English
Document type: Case Report
Document available free of charge
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Indian Journal of Pharmacology, Vol. 42, No. 4, 2010, pp. 245-246
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Diffuse skeletal pain after administration of alendronate
Ozaras, Nihal & Rezvani, Aylin
Abstract
Background : Osteoporosis is caused by bone resorption in excess of bone formation, and bisphosphonates, are used to inhibit bone resorption. Alendronate, a biphosphonate, is effective for both the treatment and prevention of osteoporosis in postmenopausal women. Side effects are relatively few and prominently gastrointestinal. Musculoskeletal pain may be an important side effect in these patients. We presented a patient admitted to our out-patient clinic with diffuse skeletal pain after three consecutive administration of alendronate.
Conclusion : We conclude that patients with osteoporosis can report pain, and bisphosphonate-related pain should also be considered before ascribing this complaint to osteoporosis.
Keywords
Alendronate, biphosphonates, bone pain, musculoskeletal, osteoporosis
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© Copyright 2010 Indian Journal of Pharmacology. Alternative site location: http://www.ijp-online.com
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