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Tropical Journal of Pharmaceutical Research
Pharmacotherapy Group, Faculty of Pharmacy, University of Benin, Benin City, Nigeria
ISSN: 1596-5996 EISSN: 1596-5996
Vol. 8, No. 2, 2009, pp. 173-179
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Bioline Code: pr09023
Full paper language: English
Document type: Review Article
Document available free of charge
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Tropical Journal of Pharmaceutical Research, Vol. 8, No. 2, 2009, pp. 173-179
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Chemical Penetration Enhancers for Transdermal Drug Delivery Systems
Pathan, Inayat Bashir & Setty, C. Mallikarjuna
Abstract
Skin as an important site of drug application for both local and systemic effects. However in skin, the stratum corneum is the main barrier for drug penetration. Penetration enhancement technology is a challenging development that would increase the number of drugs available for transdermal administration. The permeation of drug through skin can be enhanced by both chemical penetration enhancement and physical methods. In this review, we have discussed the chemical penetration enhancement technology for transdermal drug delivery as well as the probable mechanisms of action.
Keywords
Transdermal delivery; skin; chemical penetration enhancers.
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© © Pharmacotherapy Group, Faculty of Pharmacy, University of Benin, Benin City, 300001 Nigeria. Alternative site location: http://www.tjpr.org
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