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Tropical Journal of Pharmaceutical Research
Pharmacotherapy Group, Faculty of Pharmacy, University of Benin, Benin City, Nigeria
ISSN: 1596-5996 EISSN: 1596-5996
Vol. 13, No. 10, 2014, pp. 1739-1744
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Bioline Code: pr14240
Full paper language: English
Document type: Research Article
Document available free of charge
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Tropical Journal of Pharmaceutical Research, Vol. 13, No. 10, 2014, pp. 1739-1744
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Guideline for Adherence and Diabetes Control in Co- Morbid Conditions in a Tertiary Hospital in Malaysia
Iqbal, M.Z.; Khan, A.H.; Sulaiman, S.A.; Iqbal, M.S. & Hussain, Z.
Abstract
Purpose: To evaluate doctors’ adherence to Malaysian Clinical Practice Guideline (CPG) 2009 in
established diabetic patients with hypertension, dyslipidemia, renal diseases, obesity, and also to
assess factors associated with guideline adherence and diabetes mellitus control in Pulau Pinang
Hospital, Malaysia.
Method: Prescriptions written by 24 doctors for 480 established diabetic patients with hypertension,
dyslipidemia, renal diseases and obesity (20 patients per doctor) were noted. The control of the disease
and CPG adherence were noted from the selected prescriptions.
Results: Three hundred and forty nine (72.7 %) patients received guideline-compliant
pharmacotherapy. CPG adherence had statistically non-significant association (p < 0.301) with
hypertension, hypertension with dyslipidemia (p < 0.078), dyslipidemia (p < 0.061), renal diseases (p <
0.544) and obesity (p < 0.073). Two hundred and ninety nine (62.3 %) patients were at goal blood
glucose level. Diabetes Mellitus (DM) control had statistically significant association (Φ = 0.583, p <
0.001) with guideline compliance and statistically non-significant association (p < 0.066) with comorbidities
and also non-significant association (p < 0.300) with therapies.
Conclusion: Prescribing practices were fairly compliant with guidelines. Doctors poorly adhered to
guidelines in diabetic patients with hypertension, dislipidemia, renal diseases and obesity. Significantly
better diabetic control was seen in patients who were on monotherapy and guidelines-adherent therapy.
Keywords
Guidelines; Adherence; Diabetes Control; Diabetes mellitus (DM); Co-morbidities
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