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Tropical Journal of Pharmaceutical Research
Pharmacotherapy Group, Faculty of Pharmacy, University of Benin, Benin City, Nigeria
ISSN: 1596-5996 EISSN: 1596-5996
Vol. 15, No. 11, 2016, pp. 2497-2506
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Bioline Code: pr16329
Full paper language: English
Document type: Research Article
Document available free of charge
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Tropical Journal of Pharmaceutical Research, Vol. 15, No. 11, 2016, pp. 2497-2506
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Ethnobotanical, phytochemical and pharmacological properties of Crinum bulbispermum (Burm f) Milne-Redh and Schweick (Amaryllidaceae)
Maroyi, Alfred
Abstract
Purpose: To present an overview of the ethnobotany, phytochemistry and pharmacology of Crinum
bulbispermum so as to understand its importance and potential in primary healthcare systems.
Methods: A review of the literature was undertaken and an in-depth analysis of previous research on
ethnobotany, phytochemistry and pharmacology of C. bulbispermum. Literature sources included
papers published in journals, reports from international, regional and national organizations, conference
papers, books and theses. Electronic search engines such as Google, Google scholar, publishing sites
such as Elsevier, scienceDirect, BioMed Central (BMC), PubMed and other scientific database sites
such as ChemSpider, PubChem were used.
Results: Crinum bulbispermum is a popular medicinal plant in southern Africa used as remedy for
aching joints, rheumatism, kidney or bladder infections, septic sores and wounds. The chemical
composition of C. bulbispermum is dominated by various alkaloids and non-alkaloids isolated from the
bulbs, flowers, flowering stalks, leaves and roots. Major biological activities demonstrated by C.
bulbispermum include antimicrobial, antioxidant, actinociceptive, antiplasmodial activities as well as
effects on the central nervous system.
Conclusion: The widespread usage of C. bulbispermum as herbal medicine is threatening wild
populations, and this calls for conservation strategies and mechanisms for sustainable utilization of the
species.
Keywords
Actinociceptive; Amaryllidaceae; Antiplasmodial; Crinum bulbispermum; Ethnobotany; Pharmacology; Phytochemistry
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