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International Journal of Reproductive BioMedicine
Research and Clinical Center for Infertility, Shahid Sadoughi University of Medical Sciences of Yazd
ISSN: 1680-6433 EISSN: 1680-6433
Vol. 19, No. 9, 2021, pp. 761-772
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Bioline Code: rm21079
Full paper language: English
Document type: Review Article
Document available free of charge
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International Journal of Reproductive BioMedicine, Vol. 19, No. 9, 2021, pp. 761-772
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Luteal-phase support in assisted reproductive technology: An ongoing challenge
Dashti, Saeideh & Eftekhar, Maryam
Abstract
It has been shown that in controlled ovarian hyper stimulation cycles, defective luteal
phase is common. There are many protocols for improving pregnancy outcomes in
women undergoing fresh and frozen in vitro fertilization cycles. These approaches include
progesterone supplements, human chorionic gonadotropin, estradiol, gonadotropin-releasing
hormone agonist, and recombinant luteinizing hormone. The main challenge
is luteal-phase support (LPS) in cycles with gonadotropin-releasing hormone agonist
triggering. There is still controversy about the optimal component and time for starting
LPS in assisted reproductive technology cycles. This review aims to summarize the various
protocols suggested for LPS in in vitro fertilization cycles.
Keywords
Luteal-phase support; IVF; HCG; Progesterone; GnRH agonist; Recombinant LH.
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