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International Journal of Reproductive BioMedicine
Research and Clinical Center for Infertility, Shahid Sadoughi University of Medical Sciences of Yazd
ISSN: 1680-6433 EISSN: 1680-6433
Vol. 19, No. 9, 2021, pp. 781-788
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Bioline Code: rm21081
Full paper language: English
Document type: Letter to the Editor
Document available free of charge
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International Journal of Reproductive BioMedicine, Vol. 19, No. 9, 2021, pp. 781-788
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Success rate and ART outcome of microsurgical sperm extraction in non obstructive azoospermia: A retrospective study
Mirjalili, Seyed Ali Mohamad; Maleki, Hadi & Gholami, Javid
Abstract
Background: The management of non-obstructive azoospermia (NOA) disease
relies on microdissection testicular sperm extraction (micro-TESE). Few studies have
assessed the role of micro-TESE in men with NOA in our country.
Objective: The aim of the current study was to investigate the success rate of micro-TESE.
Materials and Methods: This retrospective descriptive-analytical study was conducted
on 463 men with NOA in Yazd Reproductive Sciences Institute during September 2017
through September 2019. Sperm were retrieved and frozen according to the rapid
sperm freezing protocol. After preparing the oocyte of the male partner’s spouse,
sperms were thawed and then entered the intracytoplasmic sperm injection process.
The clinical pregnancy of individuals was confirmed via ultrasound. Demographic data
were extracted from medical records.
Results: The success rate of micro-TESE was 38% and successful fertilization,
biochemical pregnancy, clinical pregnancy, and live birth were observed in 111 (85.4%),
29 (22.3%), 29 (22.3%) and 14 (10.7%) men, respectively. A significant difference
was seen between the two groups, regarding age (p = 0.01). In addition, the mean
follicle-stimulating hormone in men with positive micro-TESE was significantly lower
than in men with negative micro-TESE (p = 0.02).
Conclusion: The success of pregnancy in couples with NOA managed via micro-TESE
was significant. The study found that the success rate of micro-TESE was higher in older
men and in those with lower follicle-stimulating hormone levels.
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